Charlson Comorbidity Index and other predictors of in-hospital mortality among adults with community-acquired pneumonia

Autor: Laura Fuchs Bahlis, Luciano Passamani Diogo, Sandra Costa Fuchs
Jazyk: English<br />Portuguese
Předmět:
Zdroj: Jornal Brasileiro de Pneumologia
Druh dokumentu: article
ISSN: 1806-3756
DOI: 10.36416/1806-3756/e20200257
Popis: ABSTRACT Objective: To compare the performance of Charlson Comorbidity Index (CCI) with those of the mental Confusion, Urea, Respiratory rate, Blood pressure, and age = 65 years (CURB-65) score and the Pneumonia Severity Index (PSI) as predictors of all-cause in-hospital mortality in patients with community-acquired pneumonia (CAP). Methods: This was a cohort study involving hospitalized patients with CAP between April of 2014 and March of 2015. Clinical, laboratory, and radiological data were obtained in the ER, and the scores of CCI, CURB-65, and PSI were calculated. The performance of the models was compared using ROC curves and AUCs (95% CI). Results: Of the 459 patients evaluated, 304 met the eligibility criteria. The all-cause in-hospital mortality rate was 15.5%, and 89 (29.3%) of the patients were admitted to the ICU. The AUC for the CCI was significantly greater than those for CURB-65 and PSI (0.83 vs. 0.73 and 0.75, respectively). Conclusions: In this sample of hospitalized patients with CAP, CCI was a better predictor of all-cause in-hospital mortality than were the PSI and CURB-65.
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