Estratégias para a síntese de γ-alquilidenobutenolídeos Strategies for the synthesis of γ-alkilidenebutenolides

Autor: Luiz Cláudio Almeida Barbosa, Róbson Ricardo Teixeira, Patrícia Fontes Pinheiro, Célia Regina Álvares Maltha, Antônio Jacinto Demuner
Jazyk: English<br />Spanish; Castilian<br />Portuguese
Rok vydání: 2010
Předmět:
Zdroj: Química Nova, Vol 33, Iss 5, Pp 1163-1174 (2010)
Druh dokumentu: article
ISSN: 0100-4042
1678-7064
DOI: 10.1590/S0100-40422010000500030
Popis: α,β-unsaturated lactones possessing an alkylidene appendage group at the γ-position, are frequently termed γ-alkylidenebutenolides. Over the past decades, an increasing number of these compounds have been isolated from various natural sources. Members of this class of substances vary greatly in structural complexity and functionality. Besides that, many of them have been shown to display a wide range of biological activities. The γ-alkylidenebutenolides has attracted the attention of the organic synthetic chemists resulting in the development of a variety of process to synthesize them. This article review is concerned with the different approaches that can be utilized to prepare γ-alkylidenebutenolides.
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