Clinical predictors of recovery of COVID-19 associated-abnormal liver function test 2 months after hospital discharge

Autor: Justin Y. Lu, Scott L. Ho, Alexandra Buczek, Roman Fleysher, Wei Hou, Kristina Chacko, Tim Q. Duong
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-022-22741-9
Popis: Abstract This study investigated whether acute liver injury (ALI) persisted and identified predictors of ALI recovery [as indicated by alanine aminotransferase (ALT) level] at hospital discharge and 2 months post-discharge for 7595 hospitalized COVID-19 patients from the Montefiore Health System (03/11/2020–06/03/2021). Mild liver injury (mLI) was defined as ALT = 1.5–5 ULN, and severe livery injury (sLI) was ALT ≥ 5 ULN. Logistic regression was used to identify predictors of ALI onset and recovery. There were 4571 (60.2%), 2306 (30.4%), 718 (9.5%) patients with no liver injury (nLI), mLI and sLI, respectively. Males showed higher incidence of sLI and mLI (p
Databáze: Directory of Open Access Journals
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