Predictive value of monocyte to high-density lipoprotein cholesterol ratio and tumor markers in colorectal cancer and their relationship with clinicopathological characteristics

Autor:	Xuan Zhang, Hongyan Qin, Xiaodan Tan, Yuncong Mo, Zhenyong Li, Guofeng Huang, Zhixiao Wei
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Monocytes to high-density lipoprotein cholesterol ratio Colorectal cancer Carcinoembryonic antigen Carbohydrate antigen 199 Tumor markers Surgery RD1-811 Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	World Journal of Surgical Oncology, Vol 21, Iss 1, Pp 1-9 (2023)
Druh dokumentu:	article
ISSN:	1477-7819
DOI:	10.1186/s12957-023-03079-6
Popis:	Abstract Objective To evaluate the predictive value of monocyte (M) to high-density lipoprotein cholesterol (HDL-C) ratio (MHR) and tumor markers in colorectal cancer (CRC) and their correlation with clinicopathological characteristics. Methods Hematology test data and medical records of 202 CRC patients and 201 healthy subjects were collected retrospectively. The diagnostic efficacy of MHR was evaluated using receiver operating characteristic (ROC) curves and risk factors for CRC were analyzed by multivariate logistic regression. Results CRC patients had significantly higher M, MHR, carcinoembryonic antigen (CEA), and carbohydrate antigen 199 (CA199) levels, but significantly lower HDL-C levels than healthy controls (all P
Databáze:	Directory of Open Access Journals
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