Effect of multiple apheresis platelet donation on platelet indexes and aggregation rate in platelet donors

Autor: Juling LIANG, Yihong LUO, Chuangjin ZHUO, Yanjia CHEN, Xiaodan PANG, Weijian WU
Jazyk: čínština
Rok vydání: 2023
Předmět:
Zdroj: Zhongguo shuxue zazhi, Vol 36, Iss 9, Pp 807-810 (2023)
Druh dokumentu: article
ISSN: 1004-549X
1004-549x
DOI: 10.13303/j.cjbt.issn.1004-549x.2023.09.012&lang=en
Popis: Objective To investigate the effect of multiple apheresis platelet donation on platelet indexes and aggregation function in platelet donors, and to analyze the relationship between platelet indexes and their relationship with platelet aggregation rate. Methods A total of 83 platelet donors were randomly selected from Foshan Central Blood Station from September 2021 to October 2022, and were divided into control group (n= 9, first-time platelet donors or donors with the time interval from the last platelet donation >1 year) and study group (n= 74, repeat platelet donors or donors with the time interval from the last platelet donation ≤ 1 year) according to the times of blood donation. The study group was divided into 4 subgroups: 2-5 times group, 6-10 times group, 11-15 times group and 16 times group. The platelet count(Plt), platelet distribution width (PDW), mean platelet volume (MPV), large platelet ratio (P-LCR), and maximum platelet aggregation rate (MAR) before donation in each group were detected and analyzed. Results There were no significant differences in Plt, MPV, PDW, P-LCR and MAR between the subgroups and the control group (P>0.05), and there were no significant differences in Plt, MPV, PDW, P-LCR and MAR between each subgroup (P>0.05) .There was a positive correlation between Plt and MAR in blood donors (P
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