| Autor: |
Ahamed A. Jafar, Kaliapillai Nazeem Vijayakumar, Bathey R. Venkatraman, Govindaraj Venkatesh |
| Jazyk: |
angličtina |
| Rok vydání: |
2010 |
| Předmět: |
|
| Zdroj: |
Orbital: The Electronic Journal of Chemistry, Vol 1, Iss 4, Pp 306-309 (2010) |
| Druh dokumentu: |
article |
| ISSN: |
1984-6428 |
| DOI: |
10.17807/orbital.v1i4.77 |
| Popis: |
The reaction of o-phenylenediamine with anthranillic acid yield compound 2-(1H-benzo[d]imidazol-2-yl)aniline (AOP). The compound AOP was condensed with aromatic acid chlorides in the presence of pyridine to get compound N-(2-(1H-benzo[d]imidazol-2-yl)phenyl) benzamide (AB). Further it to then treated with PCl5 to get an intermediate compound then reacted with NaN3 to yield compound 2-(2-(5-phenyl-1H-tetrazol-1-yl)phenyl)-1H-benzo[d]imidazole (ABC). The compounds were synthesized in good yields and their structures were confirmed by IR, 1H-NMR, 13C-NMR spectral data and elemental analysis. Antimicrobial activity against bacteria and fungi was studied. The results of preliminary biological tests showed that of these compounds possess good biological activities. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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