Ethnic disparities in progression rates for sight-threatening diabetic retinopathy in diabetic eye screening: a population-based retrospective cohort study

Autor: Yue Wu, Sarah Barman, Adnan Tufail, Aaron Y Lee, Sarah A Barman, John Anderson, Aroon D Hingorani, Reecha Sofat, Christopher G Owen, Alicja R Rudnicka, Roshan Welikala, Emily Y Chew, Abraham Olvera-Barrios, Ryan Chambers, Louis Bolter, Catherine Egan, Charlotte Wahlich, Frederick L Ferris, Lakshmi Chandrasekaran, Umar Chaudhry, Alasdair N Warwick, Jiri Fajtl, Paolo Remagnino, Royce Shakespeare, Kathryn Willis
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMJ Open Diabetes Research & Care, Vol 11, Iss 6 (2023)
Druh dokumentu: article
ISSN: 2023-0036
2052-4897
DOI: 10.1136/bmjdrc-2023-003683
Popis: Introduction The English Diabetic Eye Screening Programme (DESP) offers people living with diabetes (PLD) annual eye screening. We examined incidence and determinants of sight-threatening diabetic retinopathy (STDR) in a sociodemographically diverse multi-ethnic population.Research design and methods North East London DESP cohort data (January 2012 to December 2021) with 137 591 PLD with no retinopathy, or non-STDR at baseline in one/both eyes, were used to calculate STDR incidence rates by sociodemographic factors, diabetes type, and duration. HR from Cox models examined associations with STDR.Results There were 16 388 incident STDR cases over a median of 5.4 years (IQR 2.8–8.2; STDR rate 2.214, 95% CI 2.214 to 2.215 per 100 person-years). People with no retinopathy at baseline had a lower risk of sight-threatening diabetic retinopathy (STDR) compared with those with non-STDR in one eye (HR 3.03, 95% CI 2.91 to 3.15, p
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