| Autor: |
Ibrahim Azar, Nada Al Masalmeh, Saghi Esfandiarifard, Gurjiwan Virk, Wissam Kiwan, Anthony Frank Shields, Syed Mehdi, Philip A. Philip |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Cancer Medicine, Vol 10, Iss 9, Pp 2987-2995 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2045-7634 |
| DOI: |
10.1002/cam4.3757 |
| Popis: |
Abstract Background The incidence of early‐onset colorectal cancer (EOCRC) is rising. Left‐sided colorectal cancer (LCC) is associated with better survival compared to right‐sided colon cancer (RCC) in metastatic disease. NCCN guidelines recommend the addition of EGFR inhibitors to KRAS/NRAS WT metastatic CRC originating from the left only. Whether laterality impacts survival in locoregional disease and EOCRC is of interest. Methods 65,940 CRC cases from the National VA Cancer Cube Registry (2001–2015) were studied. EOCRC (2096 cases) was defined as CRC diagnosed at |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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