Polycythemia vera in patients of beta-thalassemia trait and stress erythropoiesis

Autor:	Afaq A. Khan, Santosh G. Rathod, Sajad A. Geelani, Reshma Roshan, Javid R. Bhatt
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	beta-thalassemia trait polycythemia vera stress erythropoiesis Medicine
Zdroj:	Journal of Family Medicine and Primary Care, Vol 12, Iss 2, Pp 403-405 (2023)
Druh dokumentu:	article
ISSN:	2249-4863 2278-7135
DOI:	10.4103/jfmpc.jfmpc_1473_22
Popis:	A 70-year-old male with a known case of beta-thalassemia trait and was on yearly follow-up was found to have a hemoglobin of 14.8 g/dL, hematocrit of 47.7%, and RBC count of 6.0 × 1012/L. Total leukocyte count (TLC) was 5 × 109/L and platelet count was 4 × 109/L. Secondary causes of polycythemia were ruled out (e.g., renal or cardiac disease and smoking). He did not have symptoms of hyperviscosity syndrome. The abdominal ultrasound showed no abnormalities. On further investigation, a JAK-2 (Exon 14) mutation was detected in this patient confirming the diagnosis of polycythemia vera (PV).
Databáze:	Directory of Open Access Journals
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