Bullous Dermatosis in an End-Stage Renal Disease Patient: A Case Report and Literature Review

Autor: Zeenat Yousuf Bhat, Marwan Abu Minshar, Nashat Imran, Andrew Thompson, Yahya Osman Malik
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Case Reports in Nephrology, Vol 2016 (2016)
Druh dokumentu: article
ISSN: 2090-6641
2090-665X
DOI: 10.1155/2016/6713807
Popis: Patients with advanced chronic kidney disease including ESRD patients may present with a wide spectrum of cutaneous abnormalities, ranging from xerosis to hyperpigmentation to severe deforming necrotizing lesions. Skin problems are not uncommon in this population of patients, with a clinical presentation that can be quite bizarre, mandating a long list of differential diagnostic possibilities, and subsequent rise of a puzzling diagnostic challenge. We describe an ESRD patient who presented with blistering, nonhealing ulcerative lesions with a diagnostic skin biopsy revealing a mixed pattern of linear IgA bullous dermatosis and dermatitis herpetiformis. A clinical remission could be achieved with pulse intravenous steroids followed by oral maintenance in combination with dapsone, with no evidence of recurrence.
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