Peculiarities of Seroprovalence to SARS-CoV-2 in the Population of the Middle and Southern Urals in the Early Period of the COVID-19 Pandemic

Autor: A. Yu. Popova, E. B. Ezhlova, A. A. Melnikova, V. S. Smirnov, L. V. Lyalina, D. N. Kozlovskikh, S. V. Luchinina, S. V. Romanov, N. N. Valeullina, O. V. Dikonskaya, G. G. Chirkova, O. L. Malykh, A. V. Ponomareva, I. V. Chistyakova, A. S. Kilyachina, A. I. Yurovskikh, A. A. Kotova, A. A. Totolian
Jazyk: ruština
Rok vydání: 2021
Předmět:
Zdroj: Эпидемиология и вакцинопрофилактика, Vol 20, Iss 3, Pp 8-18 (2021)
Druh dokumentu: article
ISSN: 2073-3046
2619-0494
DOI: 10.31631/2073-3046-2021-20-3-8-18
Popis: Relevance. At the end of 2019, the world was confronted with a novel coronavirus (SARS-CoV-2), In January 2020, WHO declared an epidemic related to SARS-CoV-2, a health emergency of international importance, and in March characterized the spread of the world. diseases like a pandemic.Purpose of the study. Conduct a comparative analysis of the seroprevalence of the population of the Sverdlovsk and Chelyabinsk regions – the largest administrative territorial entities of the Middle and Southern Urals – against the backdrop of the COVID-19 pandemic.Materials and methods. The work was carried out under the program of the first stage of assessing the seroprevalence of the population of the Russian Federation according to a unified methodology developed by Rospotrebnadzor of the Russian Federation with the participation of the Saint Petersburg Pasteur Institute. The selection of participants was carried out by the method of questioning and randomization. The presence of antibodies to the SARS-CoV-2 nucleocapsid was determined in blood serum by the enzyme immunoassay.Results. Comparative analysis of the results showed that the incidence rate of COVID-19 in the Chelyabinsk region was consistently lower, and the seroprevalence at the first stage of the study was statistically significantly higher (p
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