Ameloblastic Fibrosarcoma of the Mandible: A Case Report and Brief Review of the Literature
| Autor: | Abelardo Loya-Solis, Karla Judith González-Colunga, Cynthia M. Pérez-Rodríguez, Natalie Sofía Ramírez-Ochoa, Luis Ceceñas-Falcón, Oralia Barboza-Quintana |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Case Reports in Pathology, Vol 2015 (2015) |
| Druh dokumentu: | article |
| ISSN: | 2090-6781 2090-679X |
| DOI: | 10.1155/2015/245026 |
| Popis: | Ameloblastic fibrosarcoma is an uncommon odontogenic tumor composed of a benign epithelial component and a malignant ectomesenchymal component most frequently seen in the third and fourth decades of life. It mainly presents as a painful maxillary or mandibular swelling. Radiographs show a radiolucent mass with ill-defined borders. Radical surgical excision and long-term follow-up are the suggested treatment. We report the case of a 22-year-old female with a 2-month history of an asymptomatic swelling in her left mandible. Examination revealed an exophytic growth measuring 3×3 cm extending from the mandibular left first premolar to the second molar. The patient underwent a left hemimandibular resection. Histopathological examination revealed a biphasic tumor composed of inconspicuous islands of benign odontogenic epithelium and an abundant malignant mesenchymal component with marked cellularity, nuclear pleomorphism, hyperchromatism, and moderate mitotic figures with clear margins; one year after the surgical procedure, the patient is clinically and radiologically disease-free. |
| Databáze: | Directory of Open Access Journals |
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