Prognostic value of red blood cell distribution width and D‐Dimer in diffuse large B‐cell lymphoma: Systematic review and meta‐analysis

Autor: Maryam Rahchamani, Mohammad Sedghi, Ali Hakimi, Mahdi Nejatianfar, Tohid Javaheri, Reza Tavakoli, Ramtin Ahmadi, Mansoureh Makarem, Nazanin Azmi‐Naei, Saeid Zahmatkesh Sangani, Neda Kamandi, AmirMohammad Soleimanian, Rasoul Shavaleh, Molood Foogerdi, Kazem Rahmani
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Cancer Reports, Vol 7, Iss 1, Pp n/a-n/a (2024)
Druh dokumentu: article
ISSN: 2573-8348
DOI: 10.1002/cnr2.1936
Popis: Abstract Background The significant role of red blood cell distribution width (RDW) and D‐Dimer as prognostic factors in patients with some blood malignancies has been reported recently. Aim We designed and performed a meta‐analysis to investigate the prognostic roles of RDW and D‐Dimer in subjects with diffuse large B‐cell lymphoma (DLBCL). Materials and Methods We systematically reviewed PubMed‐Medline, SCOPUS, EMBASE, Web of Science Core Collection, and Google Scholar up to the present to look for publications on prognostic effects of RDW and D‐Dimer in DLBCL patients. For investigation of the associations between RDW and D‐Dimer with the overall survival (OS) and progression‐free survival (PFS) of the DLBCL cases, hazard ratio (HR) with 95% confidence intervals (CIs) was used. Results We included 13 eligible studies in the present meta‐analysis. The results of pooled analysis showed that increased levels of RDW was related to poor OS (HR = 2.01, 95% CI: 1.62–2.48, p value
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