Interferon-β 1a and SARS Coronavirus Replication

Autor: Lisa E. Hensley, Elizabeth A. Fritz, Peter B. Jahrling, Christopher Karp, John W. Huggins, Thomas W. Geisbert
Jazyk: angličtina
Rok vydání: 2004
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 10, Iss 2, Pp 317-319 (2004)
Druh dokumentu: article
ISSN: 1080-6040
1080-6059
DOI: 10.3201/eid1002.030482
Popis: A global outbreak of severe acute respiratory syndrome (SARS) caused by a novel coronavirus began in March 2003. The rapid emergence of SARS and the substantial illness and death it caused have made it a critical public health issue. Because no effective treatments are available, an intensive effort is under way to identify and test promising antiviral drugs. Here, we report that recombinant human interferon (IFN)-β 1a potently inhibits SARS coronavirus replication in vitro.
Databáze: Directory of Open Access Journals