Health-related quality of life among blood donors with hepatitis B and hepatitis C: longitudinal study before and after diagnosis

Autor: Francisco Augusto Porto Ferreira, Cesar de Almeida-Neto, Maria Cristina Dias Teixeira, Edna Strauss
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Revista Brasileira de Hematologia e Hemoterapia, Vol 37, Iss 6, Pp 381-387 (2015)
Druh dokumentu: article
ISSN: 1806-0870
DOI: 10.1016/j.bjhh.2015.08.004
Popis: ABSTRACT Introduction: There is evidence that patients suffering from chronic hepatic diseases, including chronic hepatitis B and chronic hepatitis C, have a reduced health-related quality of life. The aim of this study was to evaluate the impact of the notification of test results for hepatitis B and hepatitis C on the quality of life of blood donors. Methods: Over a 29-month period, this study assessed the quality of life of 105 blood donors with positive serological screening tests for hepatitis B and hepatitis C and donors who presented false-positive test results. The Medical Outcome Study 36-Item Short Form Health Survey Questionnaire was applied at three time points: (1) when an additional blood sample was collected for confirmatory tests; (2) when donors were notified about their serological status; and (3) when donors, positive for hepatitis B and hepatitis C, started clinical follow- up. Quality of life scores for the confirmed hepatitis B and hepatitis C groups were compared to the false-positive control group. Results: The domains bodily pain, general health perception, social function, and mental health and the physical component improved significantly in donors with hepatitis C from Time Point 1 to Time Point 3. Health-related quality of life scores of donors diagnosed with hepatitis B and hepatitis C were significantly lower in six and four of the eight domains, respectively, compared to the false-positive control group. Conclusion: A decreased quality of life was detected before and after diagnosis in blood donors with hepatitis B and hepatitis C. Contrary to hepatitis B positive donors, the pos- sibility of medical care may have improved the quality of life among hepatitis C positive donors.
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