Effective long-term temozolomide rechallenge in a macroprolactinoma

Autor: Benedetta Zampetti, Giorgia Simonetti, Roberto Attanasio, Antonio Silvani, Renato Cozzi
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-5 (2018)
Druh dokumentu: article
ISSN: 2052-0573
DOI: 10.1530/EDM-18-0092
Popis: We describe the 20-year course of a 63-year-old male with a macroprolactinoma that acquired resistance to treatment and aggressive behavior after a 4-year successful treatment with cabergoline. He was submitted to multiple surgical resections by a skilled surgeon, fractionated radiotherapy and was eventually treated with temozolomide. After a first 6-month standard cycle, a relapse occurred and he was treated again successfully.
Databáze: Directory of Open Access Journals