Characteristics of synovial fluid in patients with juvenile idiopathic arthritis

Autor: Elena Martínez del Val, Alicia Rodríguez Martínez, Virginia Sánchez Becerra, Jaime Cruz Rojo, Eugenia Enríquez Merayo, Estefanía Barral Mena, Jaime de Inocencio Arocena
Jazyk: Spanish; Castilian
Rok vydání: 2019
Předmět:
Zdroj: Anales de Pediatría (English Edition), Vol 91, Iss 4, Pp 244-250 (2019)
Druh dokumentu: article
ISSN: 2341-2879
DOI: 10.1016/j.anpede.2019.01.011
Popis: Introduction: Synovial fluid (SF) analysis is an important tool for the diagnosis of patients with juvenile idiopathic arthritis (JIA). Patients and methods: A retrospective analysis was carried out of cytological features of SF samples obtained from patients with JIA during the period 2008–2016. Results: A total of 102 SF samples from 59 patients were analysed. JIA was more common in females (66%). The most frequent form was persistent oligoarticular JIA (52.5%). The median age at onset was 5 years (IQR 2.4–11.8). SF usually showed an inflammatory pattern (median white blood cells count 11,757/mm3; IQR 4,543–18,800), with a predominance of polymorphonuclear (PMN) cells (61%; IQR 30–75). Eight patients (14%) had white blood cells counts of less than 2000 cells/mm3, with predominance of mononuclear cells (80%), whereas 3 patients (5%) had white blood cells counts higher than 50,000 cells/mm3, with a predominance of PMN cells (90%). Synovial white blood cells count did not show significant differences among the different forms of JIA. The median synovial white blood cells count in ANA-positive patients was 20% lower than in ANA-negative (9,340 vs. 11,600/mm3; P = .23). The proportion of PMN increased with increasing levels of ESR (P
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