Determination of Vitamin B12 and Folate Compounds in Commercially Available Edible Seaweed Products

Autor: Kyohei Koseki, Ryusei Yoshimura, Koki Ido, Kiho Katsuura, Tomohiro Bito, Fumio Watanabe
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Bioscience-Elite, Vol 15, Iss 2, p 10 (2023)
Druh dokumentu: article
ISSN: 1945-0494
DOI: 10.31083/j.fbe1502010
Popis: Background: Information on the contents of both vitamin B12 and folate in edible seaweeds is limited, of which deficiencies disrupt methionine biosynthesis to accumulate homocysteine as a risk factor of cardiovascular diseases. Methods: Both vitamins were determined in commercially available edible seaweed products using high-performance liquid chromatography. Results: Dried purple laver (Neopyropia yezoensis) products contain higher levels of vitamin B12 (approximately 30–60 μg/100 g dry weight) and folate compounds (approximately 880–1300 μg/100 g dry weight) than other seaweed products, such as kombu (Saccharina japonica), hijiki (Sargassum fusiformis), and wakame (Undaria pinnatifida). 5-methyltetrahydrofolate was the major folate compound in purple laver products. 5-formyltetrahydrofolate was found at a moderate level, whereas tetrahydrofolate, 5,10-metenyltetrahydrofolate, 10-formyltetrahydrofolate, and folic acid were found to be minor folate compounds. Conclusions: These findings suggest that dried purple laver (nori) products are suitable sources of vitamin B12 and folate compounds for humans, especially vegetarians.
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