| Autor: |
Kunal Jain, Sumeet Sood, K. Gowthamarajan |
| Jazyk: |
angličtina |
| Předmět: |
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| Zdroj: |
Brazilian Journal of Infectious Diseases, Vol 17, Iss 5, Pp 579-591 |
| Druh dokumentu: |
article |
| ISSN: |
1678-4391 |
| DOI: |
10.1016/j.bjid.2013.03.004 |
| Popis: |
Cerebral malaria is the most severe and rapidly fatal neurological complication of Plasmodium falciparum infection and responsible for more than two million deaths annually. The current therapy is inadequate in terms of reducing mortality or post-treatment symptoms such as neurological and cognitive deficits. The pathophysiology of cerebral malaria is quite complex and offers a variety of targets which remain to be exploited for better therapeutic outcome. The present review discusses on the pathophysiology of cerebral malaria with particular emphasis on scope and promises of curcumin as an adjunctive therapy to improve survival and overcome neurological deficits. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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