Effect of Zinc Oxide Nanoparticles on Blood Lipid Profile in Wistar Male Rats
| Autor: | Pirooz Pour Mohammad, Reza Alipanah-Moghadam, Firooz Amani, Ali Nemati, Vadood Malekzadeh |
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| Jazyk: | perština |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Journal of Ardabil University of Medical Sciences, Vol 18, Iss 1, Pp 34-42 (2018) |
| Druh dokumentu: | article |
| ISSN: | 2228-7280 2228-7299 |
| Popis: | Background & objectives: Due to the widespread use of zinc oxide nanoparticles (ZnO-NPs) and their possible unwanted effects in biological environments, we made an attempt to investigate the effect of ZnO-NPs on the blood lipid profile. Methods: In this study, 24 male Wistar rats were used. The rats were randomly divided into three groups: control group, the group receiving ZnO-NPs at 25 mg/kg (ZnO-NPs 25 mg/kg) and the group receiving ZnO-NPs at 50 mg/kg (ZnO-NPs 50 mg/kg). The duration of the test was two weeks. The blood samples were taken and the serums were separated. Serum levels of triglyceride, cholesterol, VLDL, LDL and HDL were determined using standard kits and methods. Results: Based on the findings of this study, serum levels of triglyceride and VLDL in both ZnO-NPs receiving groups were significantly increased in comparison with the control group (p |
| Databáze: | Directory of Open Access Journals |
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