Planning in silico screening and experimental study of the hypoglycemic derivatives of cyclic guanidines

Autor:	P. M. Vasiliev, A. A. Spasov, K. V. Lenskaya, V. V. Poroikov, D. A. Filimonov, V. A. Anisimova
Jazyk:	ruština
Rok vydání:	2014
Předmět:	циклические гуанидины гипогликемическая активность методы in silico диабет компьютерное планирование экспериментов cyclic guanidines hypoglycemic activity in silico methods diabetes computer planning of experiments Medicine
Zdroj:	Кубанский научный медицинский вестник, Iss 6, Pp 11-15 (2014)
Druh dokumentu:	article
ISSN:	1608-6228 2541-9544
Popis:	This article is devoted to the search for new cyclic guanidine derivatives with hypoglycemic activity by means of in silico methods. The results of computer prediction of hypoglycemic effect for nine classes of these compounds were analyzed. Two perspective classes of cyclic guanidine derivatives have been identified. Planning in silico screening was performed and new unstudied substances were tested.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/1fee039c1de94f5381876ec166cf7484 Zobrazit plný text záznamu View record in DOAJ