The impact of isatin derivatives on antibiotic production by Streptomyces hygroscopicus CH-7

Autor: Ćirić Jovan T., Konstantinović Sandra S., Ilić Slavica B., Gojgić-Cvijović Gordana, Savić Dragiša S., Veljković Vlada B.
Jazyk: English<br />Serbian
Rok vydání: 2016
Předmět:
Zdroj: Hemijska Industrija, Vol 70, Iss 2, Pp 123-128 (2016)
Druh dokumentu: article
ISSN: 0367-598X
2217-7426
14112701
DOI: 10.2298/HEMIND141127019C
Popis: The effect of isatin derivatives as a nitrogen source on antibiotic (Hexaene H-85 and Azalomycine B) production by Streptomyces hygroscopicus CH-7 was studied. Isatin-3-hydrazone, 5-chloroisatin-3-hydrazone, isatin-3-tosylhydrazone, 5-chloroisatin-3-tosylhydrazone, isatin-3-(4`-hidroxy)benzoilhydrazone and 5-chloroisatin-3-(4`-hidroxy)benzoilhydrazone were synthesized in a crude glycerol, obtained during the biodiesel production from edible sunflower oil. The highest concentration of Hexaene H-85 is achieved with 5-chloroisatin-3-hydrazone (197 mg/cm3) in medium, while isatin-3-hydrazone has a greatest impact on Azalomycine B production (72 μg/cm3). [Projekat Ministarstva nauke Republike Srbije, br. III 45001]
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