| Autor: |
Ehsan Valavi, Azar Nickavar, Parisa Amoori, Mohsen Fathi, Bahareh Valavi |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Journal of Nephropharmacology, Vol 12, Iss 2, Pp e10571-e10571 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2345-4202 |
| DOI: |
10.34172/npj.2023.10571 |
| Popis: |
Introduction: Steroid dependent nephrotic syndrome (SDNS) is a difficult and troublesome presentation of idiopathic nephrotic syndrome (INS) in children, with complicated management and increased morbidity. Objectives: The aim of this study was to identify the predictive clinical and laboratory characteristics of patients with SDNS, for parents counseling, appropriate management and improving outcome. Patients and Methods: A total of 374 children with steroid sensitive INS were evaluated in two groups as steroid dependent (group 1=199) and non-steroid dependent (group 2= 175) INS. SDNS was defined as ≥2 relapses during steroid reducing treatment or 15 days after discontinuation of corticosteroids. Results: Mean age at presentation was significantly lower in children with SDNS than those without steroid dependency (P=0.022). Diagnostic age less than two years (P=0.016), total relapses (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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