| Autor: |
Giuseppe Celentano, Massimiliano Creta, Luigi Napolitano, Marco Abate, Roberto La Rocca, Marco Capece, Claudia Mirone, Simone Morra, Francesco Di Bello, Luigi Cirillo, Francesco Mangiapia, Gianluigi Califano, Claudia Collà Ruvolo, Caterina Sagnelli, Antonello Sica, Armando Calogero, Fabrizio Iacono, Ferdinando Fusco, Vincenzo Mirone, Nicola Longo |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Diagnostics, Vol 12, Iss 6, p 1475 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2075-4418 |
| DOI: |
10.3390/diagnostics12061475 |
| Popis: |
The management of patients with prostate cancer (PCa) and previous or synchronous colorectal cancer (CRC) represents a challenging issue. A systematic review was performed in May 2022 to summarize available evidence about the diagnosis, management, and outcomes of these patients. Twenty-seven studies involving 252 patients were identified. Overall, 163 (64.7%) and 89 (35.3%) patients had synchronous and metachronous PCa and CRC, respectively. In patients with synchronous diseases, PCa treatment involved active surveillance in 1 patient, radical prostatectomy (RP) in 36 patients, radiotherapy (RT) in 60 patients, RP plus RT in 1 patient, proton beam therapy in 1 patient, and cryoablation in 1 patient. In patients with previous CRC treatment, prostate biopsy was mostly performed by transrectal approach (n = 24). The trans-perineal and suprapubic approaches were adopted in 12 and 6 cases, respectively. Surgical PCa treatment in these cases involved endoscopic extraperitoneal RP, robot-assisted RP, and not otherwise specified RP in 30, 15, and 2 cases, respectively. Biochemical recurrence rates ranged from 20% to 28%. Non-surgical PCa treatment options included brachytherapy, RT plus androgen deprivation therapy, and RT alone in 23, 2 and 4 patients, respectively. PCa specific survival was reported by one study and was 100%. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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