Patient Perception of Negative Noninvasive Prenatal Testing Results
| Autor: | A. Theresa Wittman, S. Shahrukh Hashmi, Hector Mendez-Figueroa, Salma Nassef, Blair Stevens, Claire N. Singletary |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | American Journal of Perinatology Reports, Vol 06, Iss 04, Pp e391-e406 (2016) |
| Druh dokumentu: | article |
| ISSN: | 2157-6998 2157-7005 |
| DOI: | 10.1055/s-0036-1594243 |
| Popis: | Objective To determine patient perception of residual risk after receiving a negative non-invasive prenatal testing result. Introduction Recent technological advances have yielded a new method of prenatal screening, non-invasive prenatal testing (NIPT), which uses cell-free fetal DNA from the mother's blood to assess for aneuploidy. NIPT has much higher detection rates and positive predictive values than previous methods however, NIPT is not diagnostic. Past studies have demonstrated that patients may underestimate the limitations of prenatal screening; however, patient perception of NIPT has not yet been assessed. Methods and Materials We conducted a prospective cohort study to assess patient understanding of the residual risk for aneuploidy after receiving a negative NIPT result. Ninety-four participants who had prenatal genetic counseling and a subsequent negative NIPT were surveyed. Results There was a significant decline in general level of worry after a negative NIPT result (p = |
| Databáze: | Directory of Open Access Journals |
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