| Autor: |
Reuter Thomas, Horbert Victoria, Kinne Raimund, Hurschler Christof |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Current Directions in Biomedical Engineering, Vol 9, Iss 1, Pp 383-386 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2364-5504 |
| DOI: |
10.1515/cdbme-2023-1096 |
| Popis: |
Mechanical characteristics of hard and soft tissues are central features for the quantitative description of tissue properties. In this study, we present a biphasic 3D-FE-based method to determine the biomechanical properties of sheep stifle joint articular cartilage (load-bearing area of the medial and lateral femur condyle, n = 28) from stress relaxation indentation tests (s = 0.1 mm, t = 180 s). The FE-model computation was optimized by exploiting the axial symmetry and mesh resolution. Parameters were determined using the Levenberg-Marquardt-algorithm. Results showed significant differences between the biomechanical parameters of the lateral (n = 11) and medial (n = 17) femur condyle of the sheep stifle joint articular cartilage. R² of the fit results varied between 0.91 and 0.99. Overall values for the Young’s modulus were 1.316 ± 0.778 MPa, for the Poisson’s ratio 0.106 ± 0.088 and for the permeability 0.008 ± 0.004 mm4/Ns. Future work will focus on studying the influence of experimental settings on the results obtained with the biphasic 3D-FE-model. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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