Capecitabine from X-ray powder synchrotron data
| Autor: | Jan Rohlicek, Michal Husak, Ales Gavenda, Alexandr Jegorov, Bohumil Kratochvil, Andy Fitch |
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| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: | |
| Zdroj: | Acta Crystallographica Section E, Vol 65, Iss 6, Pp o1325-o1326 (2009) |
| Druh dokumentu: | article |
| ISSN: | 16005368 1600-5368 |
| DOI: | 10.1107/S1600536809017905 |
| Popis: | In the title compound [systematic name 5-deoxy-5-fluoro-N-(pentyloxycarbonyl)cytidine], C15H22FN3O6, the pentyl chain is disordered over two positions with refined occupancies of 0.53 (5) and 0.47 (5). The furan ring assumes an envelope conformation. In the crystal, intermolecular N—H...O hydrogen bonds link the molecules into chains propagating along the b axis. The crystal packing exhibits electrostatic interactions between the 5-fluoropyrimidin-2(1H)-one fragments of neighbouring molecules as indicated by short O...C [2.875 (3) and 2.961 (3) Å] and F...C [2.886 (3) Å] contacts. |
| Databáze: | Directory of Open Access Journals |
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