Autor: |
Ranjit D. Singh, Jeroen T. J. M. van Dijck, Thomas A. van Essen, Hester F. Lingsma, Suzanne S. Polinder, Erwin J. O. Kompanje, Erik W. van Zwet, Ewout W. Steyerberg, Godard C. W. de Ruiter, Bart Depreitere, Wilco C. Peul |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Trials, Vol 23, Iss 1, Pp 1-27 (2022) |
Druh dokumentu: |
article |
ISSN: |
1745-6215 |
DOI: |
10.1186/s13063-022-06184-1 |
Popis: |
Abstract Background The rapidly increasing number of elderly (≥ 65 years old) with TBI is accompanied by substantial medical and economic consequences. An ASDH is the most common injury in elderly with TBI and the surgical versus conservative treatment of this patient group remains an important clinical dilemma. Current BTF guidelines are not based on high-quality evidence and compliance is low, allowing for large international treatment variation. The RESET-ASDH trial is an international multicenter RCT on the (cost-)effectiveness of early neurosurgical hematoma evacuation versus initial conservative treatment in elderly with a t-ASDH Methods In total, 300 patients will be recruited from 17 Belgian and Dutch trauma centers. Patients ≥ 65 years with at first presentation a GCS ≥ 9 and a t-ASDH > 10 mm or a t-ASDH 5 mm, or a GCS |
Databáze: |
Directory of Open Access Journals |
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