Relationship of Left Ventricular Mass with BMI and Insulin Resistance in Normotensive Obese Women
| Autor: | Rengin Altınok, Füsun Erdenen, Turgut Karabağ, Feray Akbaş, Esma Altunoğlu, Fatma Eda Nuhoglu Kantarcı, Duygu Şak |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | İstanbul Medical Journal, Vol 17, Iss 4, Pp 113-117 (2016) |
| Druh dokumentu: | article |
| ISSN: | 2619-9793 2148-094X |
| DOI: | 10.5152/imj.2016.79836 |
| Popis: | Objective: Obesity is correlated with left ventricular mass (LVM) and insulin resistance (IR) and is an independent predictor of LVM in nondiabetic, non-hypertensive, obese people. Our aim was to investigate the relationship of body mass index (BMI) and IR with left venticular mass index (LVMI) in obese and nonobese, normotensive, nondiabetic women.Methods: 81 obese, normotensive, nondiabetic women and 36 healthy women of normal weight were included in the study. We compared the demographic features, biochemical values, insulin and HOMA-IR values, heart rate, blood pressure, and echocardiographic parameters of the obese and nonobese subjects.Results: The mean age was 39.3±11.2 years and the mean BMI was 39.5±5.7 kg/m2 in the obese group; the mean age was 38.4±9.5 years and the mean BMI was 22.5±1.9 kg/m2 in the control group. Hyperinsulinemia (19.3±10.4 μU/mL) and IR (HOMA-IR: 4.6±2.9) were correlated with obesity. Insulin levels and IR were associated with LWM, LWMI, aortic diameter (AD), left atrial diameter (LAD), interventricular wall thickness (IVWT), left ventricular end diastolic diameter (IVEDD), and left ventricular posterior wall thickness (LVPWT). Age, insulin value, and BMI were determinants of LVMI (p |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|