Severe late-onset ovarian hyperstimulation syndrome presenting with liver dysfunction after in vitro fertilization: A case report

Autor: Jennifer J. Chae-Kim, Robert Roman, Kristina Hawkins, Larisa Gavrilova-Jordan
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Case Reports in Women's Health, Vol 31, Iss , Pp e00332- (2021)
Druh dokumentu: article
ISSN: 2214-9112
DOI: 10.1016/j.crwh.2021.e00332
Popis: Ovarian hyperstimulation syndrome (OHSS) is a feared complication of controlled ovarian stimulation (COS) and can be associated with significant morbidity and mortality. Risk factors for OHSS include a history of OHSS, young age, low body mass index (BMI), polycystic ovary syndrome, elevated serum levels of anti-Müllerian hormone (AMH), large number of recruited follicles, elevated serum levels of estradiol, and higher gonadotropin doses during COS. However, OHSS may develop in patients with minimal risk factors. We present the case of a patient with minimal risk factors who developed severe late-onset OHSS in early pregnancy with liver dysfunction requiring hospitalization. After hospital discharge, her pregnancy resulted in a term live birth. We recommend that clinicians include OHSS in the differential diagnosis of elevated levels of liver enzymes in early pregnancy.
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