Stem cell-based therapy for ameliorating intrauterine adhesion and endometrium injury

Autor: Yu-Ting Song, Peng-Cheng Liu, Jie Tan, Chen-Yu Zou, Qian-Jin Li, Jesse Li-Ling, Hui-Qi Xie
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Druh dokumentu: article
ISSN: 1757-6512
DOI: 10.1186/s13287-021-02620-2
Popis: Abstract Intrauterine adhesion refers to endometrial repair disorders which are usually caused by uterine injury and may lead to a series of complications such as abnormal menstrual bleeding, recurrent abortion and secondary infertility. At present, therapeutic approaches to intrauterine adhesion are limited due to the lack of effective methods to promote regeneration following severe endometrial injury. Therefore, to develop new methods to prevent endometrial injury and intrauterine adhesion has become an urgent need. For severely damaged endometrium, the loss of stem cells in the endometrium may affect its regeneration. This article aimed to discuss the characteristics of various stem cells and their applications for uterine tissue regeneration.
Databáze: Directory of Open Access Journals