Janus Hydrogel Microbeads for Glucose Sensing with pH Calibration

Autor: Maru Ando, Mio Tsuchiya, Shun Itai, Tomomi Murayama, Yuta Kurashina, Yun Jung Heo, Hiroaki Onoe
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Sensors, Vol 21, Iss 14, p 4829 (2021)
Druh dokumentu: article
ISSN: 1424-8220
DOI: 10.3390/s21144829
Popis: We present fluorescent Janus hydrogel microbeads for continuous glucose sensing with pH calibration. The Janus hydrogel microbeads, that consist of fluorescent glucose and pH sensors, were fabricated with a UV-assisted centrifugal microfluidic device. The microbead can calibrate the pH values of its surroundings and enables accurate measurements of glucose within various pH conditions. As a proof of concept, we succeeded in obtaining the accurate value of glucose concentration in a body-fluid-like sample solution. We believe that our fluorescent microbeads, with pH calibration capability, could be applied to fully implantable sensors for continuous glucose monitoring.
Databáze: Directory of Open Access Journals