ADVERSE EVENTS OF INTERFERONS WITH SYSTEMIC EFFECT
| Autor: | A. A. Toporov, A. S. Kolbin |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Безопасность и риск фармакотерапии, Vol 0, Iss 2, Pp 5-11 (2018) |
| Druh dokumentu: | article |
| ISSN: | 2312-7821 2619-1164 |
| Popis: | Objective: To explore the profile of adverse events associated with interferon therapy. Design: Systematic review. Data sources: Electronic and paper records in subject area from 2000 to 2014. Methods: We searched for the studies on safety and tolerability containing adverse events of interferons with systemic effect. Results: The most frequent adverse events were: flu-like syndrome (55%), depression (30%), neutropenia (20%), anemia (13%). Conclusion: Adverse events are a very serious problem of interferon treatment. System of pharmacovigilance provides forecasting and early identification of these adverse events, as they are predictable. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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