| Autor: |
Sara Teresita Calle-Peña, Edwin David Diaz Tavara, Edwin Aguirre-Milachay, Darwin A. León-Figueroa, Mario J. Valladares-Garrido |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-9 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1471-2466 |
| DOI: |
10.1186/s12890-024-03241-0 |
| Popis: |
Abstract Objectives To determine predictors of high-flow nasal cannula (HFNC) failure in COVID-19 patients in a hospital in northern Peru. Methodology A retrospective cohort study was conducted during the months of March and May 2021. Data collection was based on a follow-up of 156 hospitalized patients with a diagnosis of COVID-19 who were users of HFNC. Epidemiological factors and clinical outcomes of treatment were analyzed from medical records. Epidemiological, analytical, and HFNC use-related characteristics were described using measures of absolute and relative frequencies, measures of central tendency, and dispersion. A multivariate Poisson regression analysis with robust variance and a 95% confidence interval was performed. Results We found that age, SpO2/FiO2, work of breathing (WOB scale) at admission, degree of involvement, type of infiltrate on CT scan, lymphocytes, c-reactive protein, and D-dimer were significantly associated with failure of HFNC (p = 60 years [RRa 1.39 (1.05–1.85)] and PaO2/FiO2 score less than 100 [Rra 1.65 (0.99–2.76)]. Conclusions Predictors to failure of HFNC are age older than 60 years and minimally significantly lower PaO2/FiO2 than 100. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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