| Autor: |
Bahar Banasaz, Sara Saadat, Davood Kalantar-Neyestanaki, Hossein Zarrinfar, Fahimeh Shakeri, Mahmood Barani, Reza Mohammadinejad, Firoozeh Mirzaee, Masumeh Ghazanfarpour |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Crescent Journal of Medical and Biological Sciences, Vol 10, Iss 4, Pp 153-160 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2148-9696 |
| DOI: |
10.34172/cjmb.2023.29 |
| Popis: |
Objectives: Helicobacter pylori is a gram-negative curved bacillus that assumes a significant role in colon cancer and children´s diseases. This study aimed to examine the association between H. pylori infection with colon cancer and children´s diseases in order to achieve a comprehensive understanding of these associations and for future works. Methods: Three main databases (i.e., Cochrane Central Register of Controlled Trials [CENTRAL], Scopus, and MEDLINE) were systematically searched by two reviewers from their inception date to 2022 in order to determine the association between the H. pylori infection with the colon cancer and children’s diseases. Results: The findings of two meta-analyses were similar regarding the positive association between the risks of colorectal neoplasm (pooled OR=0.18; 95% CI of 0.99–1.40; P>0.05) and colon neoplasia (pooled OR=0.41; 95% confidence interval 1.24–1.60; P=0.000). H. pylori was associated with an increased risk of colorectal adenoma, adenocarcinoma, and advanced adenoma. Also H. pylori infection was correlated with a high risk of iron deficiency anemia (IDA), otitis media with effusion (OME), Henoch-Schonlein purpura, and growth disorders in children. Conclusions: In sum, the H. pylori infection may have been associated with an increased risk of colorectal cancer and children’s diseases. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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