| Autor: |
Jan‐Malte Placke, Maximilian Zahn, Hannah Zillikens, Frederik Krefting, Georg C. Lodde, Lisa Zimmer, Elisabeth Livingstone, Eva Hadaschik, Antje Sucker, Alexander Roesch, Alpaslan Tasdogan, Nalini K. Srinivas, Dirk Schadendorf, Jürgen C. Becker, Selma Ugurel |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
JEADV Clinical Practice, Vol 2, Iss 4, Pp 810-818 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2768-6566 |
| DOI: |
10.1002/jvc2.231 |
| Popis: |
Abstract Background Merkel cell carcinoma (MCC) is one of the deadliest skin cancers. Despite existing national guidelines, treatment of MCC patients is not as well standardized as for more common skin cancers. Objectives The study objective was to investigate factors predisposing to favourable/unfavourable patient outcomes and to which extent guideline‐based care affects patient survival. Methods This noninterventional study investigated a monocentre real‐world patient cohort with a histologically confirmed diagnosis of MCC who presented at the skin cancer centre, University Hospital Essen. Patient and tumour characteristics (age, sex, primary localization, Merkel cell polyomavirus [MCPyV], tumour stage at initial diagnosis and primary treatment measures [surgery, radiation]) were correlated with the patient outcome in terms of recurrence‐free survival (RFS) and overall survival (OS). Results A total of 108 patients were identified. The median age of the patients was 69.9 years (range 39–88), with patients aged |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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