Transplant of SARS-CoV-2–infected Living Donor Liver: Case Report
| Autor: | Michelle C. Nguyen, MD, MPH, Eliza J. Lee, MD, Robin K. Avery, MD, M. Veronica Dioverti-Prono, MD, Shmuel Shoham, MD, Aaron A. R. Tobian, MD, PhD, Evan M. Bloch, MBChB, Ahmet Gurakar, MD, Nicole A. Rizkalla, MD, Andrew M. Cameron, MD, PhD, Elizabeth A. King, MD, PhD, Shane Ottmann, MD, Jacqueline M. Garonzik-Wang, MD, PhD, Russel N. Wesson, MBChB, Benjamin Philosophe, MD, PhD |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Transplantation Direct, Vol 7, Iss 8, p e721 (2021) |
| Druh dokumentu: | article |
| ISSN: | 2373-8731 00000000 |
| DOI: | 10.1097/TXD.0000000000001178 |
| Popis: | Given the high community prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), transplant programs will encounter SARS-CoV-2 infections in living donors or recipients in the perioperative period. There is limited data on SARS-CoV-2 viremia and organotropism beyond the respiratory tract to inform the risk of transplant transmission of SARS-CoV-2. We report a case of a living donor liver transplant recipient who received a right lobe graft from a living donor with symptomatic PCR-confirmed SARS-CoV-2 infection 3 d following donation. The donor was successfully treated with remdesivir, dexamethasone, and coronavirus disease 2019 (COVID-19) convalescent plasma. No viral transmission was identified, and both donor and recipient had excellent postoperative outcomes. |
| Databáze: | Directory of Open Access Journals |
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