Patients perspectives on drug shortages in six European hospital settings – a cross sectional study

Autor: Darija Kuruc Poje, Domagoj Kifer, Isabelle Huys, Joao Miranda, Helena Jenzer, Nenad Miljković, Torsten Hoppe-Tichy, Marcin Bochniarz, Roberto Frontini, David G Schwartz, Vesna Vujić-Aleksić, Lana Nežić, Eleni Rinaki, Leonidas Tzimis, Kim Green, Jelena Jovanić, Bojana Carić, Danijela Mandić, Katarina Vilić, Tomasz Bochenek, Vesna Bačić Vrca, Srećko Marušić
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMC Health Services Research, Vol 21, Iss 1, Pp 1-10 (2021)
Druh dokumentu: article
ISSN: 1472-6963
DOI: 10.1186/s12913-021-06721-9
Popis: Abstract Background It is known that drug shortages represent a major challenge for all stakeholders involved in the process, but there is little evidence regarding insights into patients′ awareness and perspectives. This study aimed to investigate the patients-perceived drug shortages experience and their view on outcomes in different European hospital settings. Furthermore, we wanted to explore information preferences on drug shortages. Methods A retrospective, cross sectional, a mixed method study was conducted in six European hospital settings. One hospital (H) from each of this country agreed to participate: Bosnia and Herzegovina (H-BiH), Croatia (H-CR), Germany (H-GE), Greece (H-GR), Serbia (H-SE) and Poland (H-PO). Recruitment and data collection was conducted over 27 months from November 2017 until January 2020. Overall, we surveyed 607 patients which completed paper-based questionnaire. Questions related to: general information (demographic data), basic knowledge on drug shortages, drug shortages experienced during hospitalization and information preferences on drug shortage. Differences between hospital settings were analyzed using Chi-squared test or Fisher’s exact test. For more complex contingency tables, Monte Carlo simulations (N = 2000) were applied for Fisher’s test. Post-hoc hospital-wise analyses were performed using Fisher’s exact tests. False discovery rate was controlled using the Bonferroni method. Analyses were performed using R: a language and environment for statistical computing (v 3.6.3). Results 6 % of patients reported experiences with drug shortages while hospitalized which led to a deterioration of their health. The majority of affected patients were hospitalized at hematology and/or oncology wards in H-BiH, H-PO and H-GE. H-BiH had the highest number of affected patients (18.1 %, N = 19/105, p
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