Comparison of the 12-month impact of COVID-19 and SARS on physiological capacity and health-related quality of life

Autor: Ken Ka Pang Chan, Susanna So Shan Ng, Grace Chung Yan Lui, Ho Sang Leung, Ka Tak Wong, Winnie Chiu Wing Chu, Tat On Chan, Karen Yee Shan Yiu, Eugene Yuk Keung Tso, Kin Wang To, Jenny Chun Li Ngai, Tommy Wing Ho Yip, Rachel Lai Ping Lo, Joyce Ka Ching Ng, Fanny Wai San Ko, David Shu Cheong Hui
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-12 (2023)
Druh dokumentu: article
ISSN: 1471-2466
DOI: 10.1186/s12890-023-02750-8
Popis: Abstract Background Little is known about the differences in medium to long-term recovery on spirometry, 6-minute walking distance (6MWD) and health-related quality of life (HRQoL) between COVID-19 and SARS. Methods We performed a 12-month prospective study on COVID-19 survivors. The changes in dynamic lung volumes at spirometry (%predicted FEV1, %predicted FVC), 6MWD and HRQoL at 1–3, 6 to 12 months were compared against a historical cohort of SARS survivors using the same study protocol. The residual radiological changes in HRCT in COVID-19 survivors were correlated with their functional capacity. Results 108 COVID-19 survivors of various disease severity (asymptomatic 2.9%, mild 33.3%, moderate 47.2%, severe 8.3%, critical 8.3%) were recruited. When compared with 97 SARS survivors, 108 COVID-19 survivors were older (48.1 ± 16.4 vs. 36.1 ± 9.5 years, p
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