Comparison of biochemical and immunological profile of pediatric patients with acute myeloid leukemia in relation to healthy individuals

Autor: Fabiane L.F.Z. Sanches, Taís M. Nitsch, Maria Marluce S. Vilela, Valdemiro C. Sgarbieri
Jazyk: portugalština
Rok vydání: 2015
Předmět:
Zdroj: Jornal de Pediatria (Versão em Português), Vol 91, Iss 5, Pp 478-484 (2015)
Druh dokumentu: article
ISSN: 2255-5536
DOI: 10.1016/j.jpedp.2015.07.013
Popis: Objective: To compare the biochemical and immunological profiles of pediatric patients with acute myeloid leukemia (AML) with healthy children and adolescents. Methods: This was a cross‐sectional study in which 21 therapy‐naïve patients with AML were compared with a group of 24 healthy individuals. The following data were analyzed: serum proteins, leucocytes and subgroups, erythrocytes, hematocrit, hemoglobin, platelets, cytokines in peripheral blood mononuclear cells cultures under spontaneous and BCG‐ or PHA‐stimulated conditions, immunoglobulin A. and erythrocytic glutathione. Statistical analysis was performed using SPSS software, considering as significant p‐values
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