Fatal podophyllin poisoning with multi-organ toxicity: A case report

Autor: Bhakti U Sarangi, Shridhar Jadhav, Ajay Walimbe, Manikiran Reddy, Siddhi Gawhale, R Hema Priya
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Pediatric Critical Care, Vol 10, Iss 5, Pp 231-233 (2023)
Druh dokumentu: article
ISSN: 2349-6592
2455-7099
DOI: 10.4103/jpcc.jpcc_47_23
Popis: Accidental poisoning with household products is one of the leading causes of involuntary injuries among children in low- and middle-income countries. Podophyllin poisoning is a rare and potentially fatal occurrence. The podophyllotoxin is a lipid-soluble cytotoxic compound with no antidote and its toxicity includes life-threatening neurological and multisystem complications. We report a case of a 2-year-old girl with accidental podophyllin poisoning causing multi-organ dysfunction who did not survive despite timely aggressive support and explore the possibility of early use of activated charcoal and role of extra-corporeal therapies such as hemoperfusion as a life-saving measure in such situations.
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