Successful treatment of thromboses of major arteries after ChAdOx1 nCov-19 vaccination

Autor: Yasemin Goereci, Nina N. Kleineberg, Marie Madlener, Hannah Neuschmelting, Gereon R. Fink, Clemens Warnke, Henning Stetefeld
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Neurological Research and Practice, Vol 3, Iss 1, Pp 1-4 (2021)
Druh dokumentu: article
ISSN: 2524-3489
DOI: 10.1186/s42466-021-00151-y
Popis: Abstract The ChAdOx1 nCoV-19 adenoviral vector vaccine to prevent contracting Covid-19 caused by infection with SARS-CoV-2 has been associated with vaccine-induced immune thrombotic thrombocytopenia (VITT) primarily leading to venous thromboses. Here, we report two cases of major arterial occlusions after ChAdOx1 nCov-19 vaccination, comprising a 42-year-old woman with thrombotic occlusion of the left carotid artery, and a 62-year-old man with occlusion of distal aorta and iliac arteries. Both were successfully treated with intravenous immunoglobulins and non-heparin anticoagulant agents leading to a beneficial short-term outcome of 6 weeks in case 1 and four months in case 2.
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