| Autor: |
Sang Gyun Kim, Chan Mi Park, Na Rae Lee, Jiyoung Kim, Da Hyun Lyu, Seung-Hee Park, Il Ju Choi, Wan Sik Lee, Seun Ja Park, Jae Jun Kim, Ji Hyun Kim, Chul-Hyun Lim, Joo Young Cho, Gwang Ha Kim, Yong Chan Lee, Hwoon-Yong Jung, Jun Haeng Lee, Hoon Jai Chun, Sang-Yong Seol |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Gut and Liver, Vol 12, Iss 4, Pp 402-410 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1976-2283 |
| DOI: |
10.5009/gnl17414 |
| Popis: |
Background/AimsEndoscopic submucosal dissection (ESD) has been regarded as a curative treatment for early gastric cancer (EGC) in indicated cases. The aim of this study was to evaluate the nationwide long-term clinical outcomes of ESD for EGC in Korea.Methods : A prospective multicenter cohort study was performed to evaluate the long-term efficacy of ESD for EGC within pre-defined indications at 12 institutes in Korea. The cases that met the expanded criteria upon pathological review after ESD were followed for 5 years. The primary outcome was 5-year disease specific free survival.Results : Six hundred ninety-seven patients with 722 EGCs treated with ESD were prospectively enrolled and followed for 5 years. Complete resection was achieved in 81.3% of the cases, and curative resection was achieved in 86.1%. During the 5-year follow-up, the overall survival rate was 96.6%, and the disease specific free survival rate was 90.6%. Local recurrence developed in 0.9%, and metachronous tumor development occurred in 7.8%; both conditions were treated by endoscopic or surgical treatment. Distant metastasis developed in 0.5% during follow-up.Conclusion : sESD showed excellent long-term clinical outcomes and can be accepted as a curative treatment for patients with EGC who meet the expanded criteria in final pathology studies. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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