Retrograde ejaculation as an initial presenting symptom of type 2 diabetes mellitus: a case report and literature review

Autor: Yu-Shan Mao, Ning-Jun Fang, Zhi-Ren Sheng, Yi-Feng Mai
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Men's Health, Vol 18, Iss 3, p 058 (2022)
Druh dokumentu: article
ISSN: 1875-6859
DOI: 10.31083/jomh.2021.114
Popis: Retrograde ejaculation (RE), known as one of the late complications of diabetes mellitus, is rarely a presenting symptom in the diagnosis of diabetes. A 30-year-old male presented with a progressive decline in ejaculate over 2-month. Lab results revealed a high random blood glucose level (425 mg/dL). A substantial number of sperm were found in the post-ejaculate urine specimens, confirming a diagnosis of RE. Further lab tests revealed an hemoglobin-A1c (HbA1c) of 12.7%, with negative results for antibodies to glutamic acid decarboxylase, insulin antigen-2, insulin receptor and islet cell, consistent with a diagnosis of type 2 diabetes mellitus (T2DM). Insulin glargine and oral anti-hyperglycemic agents were initiated. Also, imipramine and pseudoephedrine were prescribed for 4-week and then discontinued, as no positive effect on ejaculation was seen. At the 36-month follow-up, the patient had a normal glucose level with HbA1c
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