Advances in superparamagnetic iron oxide nanoparticles modified with branched polyethyleneimine for multimodal imaging

Autor: Qiaoling Shen, Chunjing Yu
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Bioengineering and Biotechnology, Vol 11 (2024)
Druh dokumentu: article
ISSN: 2296-4185
DOI: 10.3389/fbioe.2023.1323316
Popis: Multimodal imaging are approaches which combines multiple imaging techniques to obtain multi-aspect information of a target through different imaging modalities, thereby greatly improve the accuracy and comprehensiveness of imaging. Superparamagnetic iron oxide nanoparticles (SPIONs) modified with branched polyethyleneimine have revealed good biocompatibility and stability, high drug loading capacity and nucleic acid transfection efficiency. SPIONs have been developed as functionalized platforms which can be further modified to enhance their functionalities. Those further modifications facilitate the application of SPIONs in multimodal imaging. In this review, we discuss the methods, advantages, applications, and prospects of BPEI-modified SPIONs in multimodal imaging.
Databáze: Directory of Open Access Journals