Correlation between Systemic Arterial Hypertension and Bone Morphogenetic Protein-2 in Central Obese Non-Diabetic Men with Evidence of Coronary Artery Calcification
| Autor: | Antonia Anna Lukito, Allen Widyasanto, Trilis Yulianti, Rusli Muljadi, Andi Wijaya, Peter Kabo, Syakib Bakri |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Indonesian Biomedical Journal, Vol 3, Iss 3, Pp 185-90 (2011) |
| Druh dokumentu: | article |
| ISSN: | 2085-3297 2355-9179 |
| DOI: | 10.18585/inabj.v3i3.149 |
| Popis: | BACKGROUND: Previous studies have confirmed separately the relationship between obesity, insulin-resistance, hypertension and bone morphogenetic protein-2 (BMP-2) with coronary artery calcification, a parameter of subclinical atherosclerosis. It was also reported that BMPs may function as proinflammatory, prohypertensive and proatherogenic mediators. The study aimed to assess the correlation between systemic hypertension and BMP-2 plasma concentration in central-obese non-diabetic men with evidence of coronary artery calcification. METHODS: This was a cross sectional study on 60 central-obese non-diabetic men, of an average age of 55.2 years, with evidence of coronary calcification, who came for health check-up and met the inclusion criteria consecutively as defined by waist circumference >90 cm and fasting blood glucose |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|