Acquired Factor VII Deficiency Associated With Chronic Myeloid Leukemia Blast Crisis

Autor: Emily B. Wolf MD, David Li MD, Andre J. Fernandez MPAS, PA-C, Lindsay B. Gardner MD, Candido E. Rivera MD, Ewa M. Wysokinska MD, Marwan E. Shaikh MD, Han W. Tun MD, Vivek Roy MD, Muhamad Alhaj Moustafa MD
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Investigative Medicine High Impact Case Reports, Vol 11 (2023)
Druh dokumentu: article
ISSN: 2324-7096
23247096
DOI: 10.1177/23247096231209543
Popis: Factor VII (FVII) is an important, vitamin K-dependent clotting factor. Acquired FVII deficiency is a rare entity that is associated with serious bleeding complications. We report a case of acquired FVII deficiency in a patient with recurrent chronic myeloid leukemia in blast crisis who developed bilateral retinal hemorrhages. The coagulopathy was corrected with the initiation of chemotherapy and subsequent reduction in peripheral blast count.
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