Sexual health of women using combined oral contraceptive containing estetrol and drospirenone: A prospective observational study

Autor: Mekan R. Orazov, Viktor E. Radzinskiy, Marina B. Khamoshina, Roman E. Orekhov, Vasily V. Ermakov
Jazyk: ruština
Rok vydání: 2024
Předmět:
Zdroj: Гинекология, Vol 26, Iss 1, Pp 28-34 (2024)
Druh dokumentu: article
ISSN: 2079-5696
2079-5831
20795696
DOI: 10.26442/20795696.2024.1.202568
Popis: Aim. To evaluate the effect of a combined oral contraceptive (COC) containing estetrol and drospirenone on the sexual function of women using it. Materials and methods. A total of 251 women aged 21–35 years (mean age, 25.30±2.82 years) referred for contraceptive fitting were included in the study (ICD-10: Z30.0 General contraceptive advice and counseling, Z30.4 Contraceptive drug monitoring). Women in the study cohort used the original formulation containing 15 mg estetrol and 3 mg drospirenone in a 24+4 regimen for contraceptive purposes, according to the current instructions. All female participants (n=251) were assessed for sexual function at baseline, 6 and 12 months using FSFI (The Female Sexual Function Index), FSDS-R (The Female Sexual Distress Scale-Revised) and SQoL-F (The Sexual Quality of Life-Female) scales. Study design. An open, independent, prospective observational study. Results. Women taking COC containing estetrol 15 mg and drospirenone 3 mg maintained a baseline high level of sexual satisfaction (p0.05) throughout the study, as assessed by FSFI, SQoL-F and FSDS-R scales. Conclusion. The results obtained indicate that there is no negative effect of COC containing 15 mg estetrol and 3 mg drospirenonone on the sexual function of women. High contraceptive efficacy of the drug was confirmed.
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