Oxidative metabolism may be associated with negative symptoms in schizophrenia

Autor:	Mehmet Gunes, Abdurrahman Altindag, Mahmut Bulut, Suleyman Demir, Aslihan Okan Ibiloglu, Mehmet Cemal Kaya, Abdullah Atli, Nurten Aksoy
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	Schizophrenia negative symptoms antipsychotic usage oxidative stress Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Zdroj:	Psychiatry and Clinical Psychopharmacology, Vol 27, Iss 1, Pp 54-61 (2017)
Druh dokumentu:	article
ISSN:	2475-0573 2475-0581 24750573
DOI:	10.1080/24750573.2017.1293243
Popis:	Objective: In the present study, we aimed to examine the relationship between the oxidative metabolism with disease severity, sociodemographic, and clinical characteristics in the patients with schizophrenia. Methods: Seventy-one patients with schizophrenia and 76 healthy volunteers were included in the study. Plasma total antioxidant level (TAL) and total oxidant level (TOL) were analyzed, and oxidative stress index (OSI) was calculated. Results: There was a statistically significant increase in TOL and OSI and decrease in TAL in the patients with schizophrenia compared to the controls (p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/d126ca10b0464a7ba75d0261a34683c8 Zobrazit plný text záznamu View record in DOAJ