Development of ocular hypertension secondary to tamponade with light versus heavy silicone oil: A systematic review
| Autor: | Vito Romano, Mario Cruciani, Francesco Semeraro, Ciro Costagliola, Mario R Romano |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Intraocular
lymphoma retina vitreous Conjunctiva cornea melanoma ocular surface ocular surface squamous neoplasia tumor Brachytherapy chemotherapy cryopexy intra ocular tumors photocoagulation Animal uveitis model cytomegalovirus retinitis animal model endotoxin-induced uveitis experimental autoimmune uveitis spontaneous tubercular uveitis animal model India genetics retinoblastoma review Glaucoma heavy silicone oil light silicone oil ocular hypertension retinal detachment standard silicone oil Ophthalmology RE1-994 |
| Zdroj: | Indian Journal of Ophthalmology, Vol 63, Iss 3, Pp 227-232 (2015) |
| Druh dokumentu: | article |
| ISSN: | 0301-4738 1998-3689 |
| DOI: | 10.4103/0301-4738.156922 |
| Popis: | Aim: The intraocular silicone oil (SO) tamponades used in the treatment of retinal detachment (RD) have been associated with a difference ocular hypertension (OH) rate. To clarify, if this complication was associated to use of standard SO (SSO) versus heavy SO (HSO), we performed a systematic review and meta-analysis of comparative study between two kind of SO (standard or light vs. heavy) for the treatment of RD and macular hole, without restriction to study design. Materials and Methods: The methodological quality of two randomized clinical trials (RCTs) were evaluated using the criteria given in the Cochrane Handbook for Systematic Reviews of Intervention, while three non-RCTs were assessed with the Newcastle-Ottawa Scale and Strengthening the Reporting of Observational Studies in Epidemiology checklists. We calculated Mantel-Haenszel risk ratio (RR) with 95% confidence intervals (95% CIs). The primary outcome was the rate of patients with OH treated with SSO compared to HSO. Results: There were a higher number of rates of OH in HSO compared to SSO. This difference was statistically significant with the fixed effect model (Mantel-Haenszel RR; 1.55; 95% CI, 1.06-2.28; P = 0.02) while there was not significative difference with the random effect model (Mantel-Haenszel RR; 1.51; 95% CI, 0.98-2.33; P = 0.06). Conclusion: We noted a trend that points out a higher OH rate in HSO group compared to SSO, but this finding, due to the small size and variable design of studies, needs to be confirmed in well-designed and large size RCTs. |
| Databáze: | Directory of Open Access Journals |
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